Oncopeptides presents new data at the European Haematology Association meeting
Oncopeptides AB (publ) (Nasdaq Stockholm: ONCO), a biotech company focused on research, development, and commercialization of therapies for difficult-to-treat hematological diseases, today announces that final efficacy and safety data from the ANCHOR study has been accepted as a poster presentation at the European Hematology Association meeting (EHA) in Frankfurt, Germany on June 9, 2023.
An abstract including key data is available on the following link: EHA Open Access Library.
ANCHOR is a phase 1/2 open label multicenter study evaluating the safety and efficacy of melflufen plus dexamethasone in combination with either daratumumab or bortezomib in patients with relapsed refractory multiple myeloma (RRMM). The study started in April 2018 and was prematurely closed in February 2022 with 56 patients enrolled. The final analysis continues to support the previously reported efficacy and safety data that subsequently led to the initiation of the confirmatory phase 3 LIGHTHOUSE trial. Data from the LIGHTHOUSE study was recently presented at the European Myeloma Network meeting.
“The triplet combination of melflufen plus dexamethasone and daratumumab or bortezomib, showed encouraging clinical activity in patients with RRMM who previously have received 1-4 prior lines of therapy,” says Enrique M. Ocio, University Hospital Marqués de Valdecilla (IDIVAL), University of Cantabria, Santander, Spain. “The triplet combinations with melflufen showed a predictable and manageable safety profile, which are important factors for patients in later lines of therapies.”
|Scientific abstract||First author||Abstract code|
|ANCHOR (op-104): melflufen plus dexamethasone and daratumumab or bortezomib in relapsed/refractory multiple myeloma—final efficacy and safety results.||Prof. Enrique M. Ocio, University Hospital Marqués de Valdecilla (IDIVAL), University of Cantabria, Santander, Spain.||P876|